The concomitant use of METHADOSE with all cytochrome P450 3A4, 2B6, 2C19, 2C9 or 2D6 inhibitors may possibly bring about an increase in methadone plasma concentrations, which could cause likely deadly respiratory despair. In addition, discontinuation of concomitantly made use of cytochrome P450 3A4, 2B6, 2C19, or 2C9 inducers may end in an increase… Read More